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D TAN Brightening Cream | Use 10 Days and Get Miracle Results
D TAN Brightening Cream | Use 10 Days and Get Miracle Results
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30 Days Return
Made in PAK
There are 4 Active ingredients in D TAN Brightening Cream
Alpha Arbutin 1%
Niacinamide 2% (Vitamin B3)
Kojic Acid 1%
Glutathione 1%
(No steroids and any harm full chemical Composition In this Cream. Use just 10 Days and Get visible results of whitening)
Benefits
Visibly brighten the complexion
Fade dark spots and post-acne marks
Even out skin tone
Provide antioxidant protection
Strengthen the skin barrier
Deliver smoother, healthier, and more radiant skin overall
Details of all Ingredients
1. Alpha Arbutin (1%)
Chemical nature: Hydroquinone B D glucopyranoside
Mechanism of action:
Alpha Arbutin inhibits tyrosinase, the key enzyme responsible for converting L-tyrosine into L-DOPA and then melanin.
By binding to the active site of tyrosinase, it reduces melanin synthesis, thereby limiting pigment formation in melanocytes.
The α-form (alpha arbutin) has higher stability and bioavailability compared to β-arbutin, providing more consistent depigmenting results.
It also releases small amounts of hydroquinone slowly, offering controlled depigmentation without the irritation associated with direct hydroquinone use.
Scientific benefits:
Reduces hyperpigmentation, melasma, freckles, and age spots.
Promotes uniform skin tone through regulated melanogenesis inhibition.
Provides mild antioxidant protection against UV-induced oxidative stress.
2. Niacinamide (2%) (Vitamin B3)
Chemical nature: Nicotinamide a water-soluble form of Vitamin B3
Mechanism of action:
Niacinamide serves as a precursor for NAD⁺ and NADP⁺, essential coenzymes in cellular metabolism and energy transfer.
Enhances keratinocyte differentiation and stimulates ceramide synthesis, improving the skin’s lipid barrier.
Reduces transepidermal water loss (TEWL) and boosts skin hydration.
Downregulates melanosome transfer from melanocytes to keratinocytes, resulting in visible skin tone improvement and reduced blotchiness.
Exhibits anti-inflammatory activity by suppressing IL-6 and IL-8 cytokines, beneficial for acne and rosacea-prone skin.
Scientific benefits:
Improves skin barrier integrity and elasticity.
Reduces inflammatory acne lesions and erythema.
Decreases appearance of pores and fine lines through sebum regulation.
Brightens and evens out skin tone by modulating pigment transfer.
3. Kojic Acid (1%)
Chemical nature: A natural chelation agent produced by fungi (Aspergillus, Penicillium, Acetobacter species).
Mechanism of action:
Kojic acid acts as a competitive inhibitor of tyrosinase by chelating the copper ions at its active site, disrupting the oxidation of tyrosine to DOPAquinone.
This results in reduced melanin polymer formation and, consequently, lighter pigmentation.
Kojic acid also possesses antioxidant and antibacterial properties, helping reduce oxidative stress and post-inflammatory pigmentation from acne.
Scientific benefits:
Lightens hyperpigmented lesions and dark spots.
Improves dullness by inhibiting melanogenesis.
Provides mild antimicrobial action, beneficial in acne-prone skin.
When used with arbutin and glutathione, enhances depigmenting efficacy through multiple points of melanin suppression.
4. Glutathione (1%)
Chemical nature: Tripeptide composed of glutamic acid, cysteine, and glycine.
Mechanism of action:
Glutathione is a master antioxidant that neutralizes reactive oxygen species (ROS) and protects cellular components from oxidative stress.
It modulates melanogenesis by two key mechanisms:
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Inhibition of tyrosinase activity (direct binding to copper sites).
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Shifting melanin synthesis from eumelanin (dark pigment) to pheomelanin (lighter pigment).
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Enhances detoxification in skin cells by conjugating toxins through the glutathione S-transferase pathway.
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Promotes regeneration of other antioxidants such as vitamins C and E, amplifying overall antioxidant defense.
Scientific benefits:
Brightens skin by reducing dark melanin formation.
Provides protection against UV-induced free radical damage.
Supports anti-aging by maintaining cellular redox balance and collagen structure.
Improves overall skin clarity and luminosity.
⚗️ SYNERGISTIC INTERACTION
When used together in a formulation:
Alpha Arbutin + Kojic Acid: Dual inhibition of tyrosinase through substrate competition and copper chelation synergistically reduces melanin production.
Niacinamide + Arbutin/Kojic Acid: Niacinamide decreases pigment transfer to keratinocytes, complementing the pigment-suppressing action of the other two ingredients.
Glutathione + Kojic Acid: Enhances antioxidant defense while promoting lighter pheomelanin formation, giving a more radiant skin tone.
Overall effect: Multilevel control of pigmentation pathways from melanin synthesis inhibition to reduced transfer and oxidative protection resulting in visible brightening, even tone, and improved skin texture.
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